Food-grade carrageenans and their implications in health and disease

Food additives, often used to guarantee the texture, shelf-life, taste, and appearance of processed foods, have gained widespread attention due to their increased link to the growing incidence of chronic diseases. As one of the most common additives, carrageenans have been used in human diets for hundreds of years. While classified as generally recognized as safe (GRAS) for human consumption, numerous studies since the 1980s have suggested that carrageenans, particularly those with random coil conformations, may have adverse effects on gastrointestinal health, including aggravating intestinal inflammation. While these studies have provided some evidence of adverse effects, the topic is still controversial. Some have suggested that the negative consequence of the consumption of carrageenans may be structure dependent. Furthermore, pre-existing conditions may predispose individuals to varied outcomes of carrageenan intake. In this review, structure–function relationships of various carrageenans in the context of food safety are discussed. We reviewed the molecular mechanisms by which carrageenans exert their biological effects. We summarized the findings associated with carrageenan intake in animal models and clinical trials. Moreover, we examined the interactions between carrageenans and the gut microbiome in the pathogenesis of gastrointestinal disorders. This review argues for personalized guidance on carrageenan intake based on individuals’ health status. Future research efforts that aim to close the knowledge gap on the effect of low-dose and chronic carrageenan intake as well as interactions among food additives should be conducive to the improved safety profile of carrageenans in processed food products.     

Strain-rate-dependent constitutive and damage models for a low-yielding-strength steel under dynamic loadings

Journal of Mechanical Science and Technology - The low-yielding-strength (LYS) steel is promising for energy-absorbing devices due to its outstanding plasticity. Although the mechanical properties...     

新型胶轮机车运行方式在大坡度盾构隧道施工中的应用

在传统地铁隧道施工中,有轨机车为主要运输方式,近年来有少量项目采用多功能胶轮机车运送施工材料。本文依托莫斯科地铁第三换乘环线东段大直径盾构项目案例,介绍胶轮机车的结构特点、使用优势、弧面运行时的轮胎保护措施。实践证明,胶轮机车在地铁隧道施工中具有很好的技术经济性,改进后的运行方式使其在管片弧面运行时性能更稳定。     

土木工程施工管理中常见问题及对策

在交通工程体系中,桥梁已经成为常见的工程项目,而桥梁工程的质量不仅与施工管理有关,与土木工程的施工质量也有直接的联系.文章在土木工程施工管理的基础上,分析其中常见的问题,并且提出对策,以期为当前土木工程的质量优化提供参考.     

Study of neutron production and moderation for sulfur neutron capture therapy

Neutron capture therapy with Sulfur-33, similar to boron neutron capture therapy with Boron-10, is effective in treating some types of tumors including ocular melanoma. The key point in sulfur neutron capture therapy is whether the neutron beam flux and the resonance capture cross section of ~(33)S(n;α)~(30) Si reaction at 13.5 keV can achieve the requirements of radiotherapy. In this research,the authors investigated the production of 13.5 keV neutron production and moderation based on an accelerator neutron source. A lithium glass detector was used to measure the neutron flux produced via near threshold~7 Li(p,n)~7 Be reaction using the time-of-flight method. Furthermore, the moderation effects of different kinds of materials were investigated using Monte Carlo simulation.     

核电厂应急监测计划的关键问题及探讨

应急监测计划是核电厂应急计划的重要支持性文件,是核电厂应急监测准备和响应的重要依据。本文从核电厂事故应急监测方案、监测方法、监测设施设备配置、应急监测响应、监测能力的保持、质量保证等关键问题进行分析研究,提出相关建议,为核电厂应急监测计划的制订提供参考。     

某企业不同工种的放射工作人员发生甲状腺结节风险分析

采用职业健康体检资料和问卷形式,利用单因素和多因素logistic回归模型,分析探讨某企业内不同工种的放射工作人员暴露在低剂量电离辐射环境下发生甲状腺结节的风险。结果表明,放射工作人员中以混合射线组甲状腺结节发生风险最高,随着年龄和放射工龄的增加发生风险会增加;性别不同与甲状腺结节发生风险有关。     

Docker容器化下的遥感算法程序集成方法

目的 近年来，随着我国遥感技术的快速发展，遥感数据呈现出大数据的特点，遥感数据的时效性增强，针对新环境下遥感算法编程语言众多，程序运行和部署环境需求多样，程序的集成和部署困难的问题，提出了一种遥感算法程序快速封装与Docker容器化系统集成架构。方法 该系统架构主要包括：1）遥感算法程序的镜像自动化封装制作；2）镜像的分发管理，达到算法程序镜像的共享；3）遥感信息产品生产流程的容器化编排服务，将相关联的算法程序镜像串联，以满足特定遥感信息产品的生产；4）容器的调度运行，调用镜像，实现特定遥感产品的容器化运行。本文在上述容器化系统集成架构下，以Landsat5数据的NDVI、NDWI信息产品的生产作为容器化生产实例，并同物理机、KVM （kernel-based virtual machine）虚拟机在运行时间、内存占用量、部署效率等性能进行了对比。结果 Docker容器虚拟化环境下的产品生产和物理机环境下在运行时间和内存占用量上几无差别，优于KVM虚拟机。Docker容器虚拟化环境和KVM虚拟机环境下在部署上能够节省大量时间，相比于物理机环境能够提高部署效率。结论 容器化的系统集成方式能够有效解决遥感算法程序集成和部署困难的问题，有利于遥感算法程序的复用和流程的共享，提高系统集成效率，具备较强的遥感数据实时快速处理能力。     

Association between patient psychosocial characteristics and receipt of in‐center nocturnal hemodialysis among prevalent dialysis patients

Introduction: Compared to traditional in‐center hemodialysis (HD), in‐center nocturnal dialysis (INHD) is characterized by longer sessions and nighttime administration, which may lead to better outcomes for some patients. Given the importance of patient choice in the decision to initiate INHD, we explored associations between patients’ psychosocial characteristics and their receipt of INHD. Methods: Among hemodialysis patients at a medium‐sized dialysis organization, we identified INHD patients as those for whom ≥80% of dialysis sessions were INHD sessions—starting at 6:30 pm or later and lasting ≥5 hours—over the 3 months (≥20 sessions total) after their first INHD session. We extracted dialysis session data from electronic medical records and psychosocial data from social worker assessments. We tested associations of patients’ psychosocial characteristics—as well as demographic and clinical characteristics—with INHD receipt among all hemodialysis patients (INHD and HD) in bivariate analyses and multivariable logistic regression models. Findings: Among 759 patients with complete data, we identified 47 (6.2%) as INHD patients. On average, these patients were more likely than HD patients to be employed (full‐time 10.6% vs. 5.2%; part‐time 17.0% vs. 4.2%; P < 0.001), and they were significantly less likely to require ambulatory assistance (14.9% vs. 39.6%, P < 0.001). In multivariable regressions, we found that part‐time employment (versus being unemployed) was associated with a 7.1 percentage‐point higher likelihood of being an INHD patient (P = 0.01), and the negative association with ambulatory assistance needs approached statistical significance (P = 0.056). No other psychosocial factors included in this main regression analysis were statistically significantly associated with INHD patient status. Discussion: Researchers comparing the outcomes of patients undergoing INHD versus other treatment modalities will need to account for differences in employment status—and other factors like requiring ambulatory assistance and age which may predict the ability to work—between INHD users and comparison patients to avoid bias in estimates.     

Selective clustering for representative paintings selection

Multimedia Tools and Applications - Selective classification (or rejection based classification) has been proved useful in many applications. In this paper we describe a selective clustering...